Otilonium bromide
Otilonium bromide is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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ATC Codes
A: Alimentary tract and metabolism drugs
— A03: Drugs for functional gastrointestinal disorders
— A03A: Drugs for functional gastrointestinal disorders
— A03AB: Synthetic anticholinergics, quaternary ammonium compounds for functional gastrointestinal disorders
— A03AB06: Otilonium bromide
— A03C: Antispasmodics in combination with psycholeptics
— A03CA: Synthetic anticholinergic agents in combination with psycholeptics
— A03CA04: Otilonium bromide and psycholeptics
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Clinical
Clinical Trials
4 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Irritable bowel syndrome | D043183 | EFO_0000555 | K58 | — | — | — | 2 | 1 | 3 |
| Syndrome | D013577 | — | — | — | — | — | 2 | 1 | 3 |
| Gastroscopy | D005773 | — | — | — | — | — | 1 | — | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Otilonium bromide |
| INN | otilonium bromide |
| Description | Otilonium bromide, sold under the trade name Spasmomen among others, is an antimuscarinic and calcium channel blocker used to relieve spasmodic pain of the gut, especially in irritable bowel syndrome. This means it works in the gut themselves, by relaxing the small muscles of the intestines, which results in relieving cramps and therefore reduces pain.
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| Classification | Small molecule |
| Drug class | quaternary ammonium derivatives; quaternary ammonium derivatives |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CCCCCCCCOc1ccccc1C(=O)Nc1ccc(C(=O)OCC[N+](C)(CC)CC)cc1.[Br-] |
Identifiers
| PDB | — |
| CAS-ID | 26095-59-0 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2103773 |
| ChEBI ID | — |
| PubChem CID | 72092 |
| DrugBank | — |
| UNII ID | 21HN3N72PV (ChemIDplus, GSRS) |
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Safety
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33 adverse events reported
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